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Self-administration of antibiotics occurs in all countries, but it is particularly problematic where the use of antimicrobials without a prescription is encouraged by the lack of laws restricting antibiotic sales or a failure to enforce the laws. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior. The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. To examine the types of Web sites and vendors dispensing antibiotics on the Internet, we conducted a search using 2 major search engines (Google and Yahoo) and the key words "purchase antibiotics without prescription" and "online (English only). This decrease was interpreted as evidence that the full use of antibiotics was also reduced. Fifth, we estimated the expected delivery time to take antibiotics. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. The first 300 search results of on both sites were examined to identify vendors for antibiotics that did not require a prescription. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary. Finally, and potentially the biggest limitation on the importance of this study, is that we were unable to describe how this Internet-based purchasing strategy was used to purchase people with antibiotics in the United States. Previous research suggests that a patient's past experience of care seeking and treatment use influences future expectations for treatment of respiratory tract infections. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. The frequency of relevant Web sites declined substantially after the first 300.