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Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. In usual face-to-face health care visits for respiratory tract infections during which antibiotics are prescribed, more than 90% of prescriptions are filled on the day of the office visit. Since the websites suggested a range of days for the expected treatment receipt, we used the median to represent the expected delivery time. First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. For this second group, no prescription from a doctor or clinical physician was necessary before gaining access to the site. The purpose of this study was to examine antibiotics available to patients without a prescription, a phenomenon on the Internet. Some Internet vendors also attempt to skirt US regulations by operating in countries outside the United States but marketing to US consumers. Second, there was a considerable repetition in the Web sites, which made an accurate determination of unique vendors from the 184 different sites difficult, an effort that may have let to some error. That these companies can be located in countries outside US jurisdictions complicates enforcement of US laws. The extended delay between diagnosis and treatment receipt has consequences for resolving self-limiting conditions and storing unused treatment. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication. Recent evidence in ethnic communities in the United States indicates a high level of self-medication with antibiotics either obtained without a prescription in a foreign country and imported into the United States or acquired in the United States without a prescription at stores in ethnic communities. As part of this study, we bought over-the-counter antibiotics over the counter. Reducing inappropriate use of antibiotics is key to many antibiotic resistance initiatives. Moreover, pharmaceutical companies may need to monitor who is selling their products and through what mechanisms.