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The medical community and the public health and regulating agencies, as well as pharmaceutical companies, need to expand efforts to control antibiotic resistance beyond initiatives centered on prescribing behavior to include self-medication and sources of antibiotics obtained without prescription. The vendors identified in this study do not appear to be fearful of prosecution. This phenomenon has not been the focus of initiatives to control antibiotic resistance. Most initiatives, however, focus almost exclusively on controlling prescribing by health care clinicians and do not focus on patient self-medication. This decrease was interpreted as evidence that the full use of antibiotics was also reduced. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents. The first 300 search results of on both sites were examined to identify vendors for antibiotics that did not require a prescription. Although excessive consumption of antibiotics has contributed to the spread of antibiotic resistance, 4-6 most initiatives regarding inappropriate direct human consumption of the antibiotic therapy center are almost exclusively controlled by prescribing by healthcare clinicians. Second, there was a considerable repetition in the Web sites, which made an accurate determination of unique vendors from the 184 different sites difficult, an effort that may have let to some error. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. Fifth, we estimated the expected delivery time to take antibiotics. Our final list of URLs included 184 links to single vendors of antibiotics. Unfortunately, other disturbing evidence suggests that this problem may not be easily fixed through education, a troubling issue in controlling antibiotic use. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed.