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Reducing inappropriate use of antibiotics is key to many antibiotic resistance initiatives. Several studies suggest that antibiotic prescribing for viral illnesses, respiratory tract infections being one example, has declined in the last decade. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. Although the vast majority of websites were in English, some were in other languages. Our purchase arrived from Mexico with no information on instructions for use of the medication. Although more than half of the identified sites provided online consultation for prescribing, the lack of interaction between the patient and the doctor did not lead to any opportunity for patient education. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior. Fourth, we have limited our count to English language websites. Our final list of URLs included 184 links to single vendors of antibiotics. As part of this study, we bought over-the-counter antibiotics over the counter. In usual face-to-face health care visits for respiratory tract infections during which antibiotics are prescribed, more than 90% of prescriptions are filled on the day of the office visit. There are several limitations to this study. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. This activity suggests that some vendors are aware of the questionable legitimacy of their business.