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This reservoir of antibiotics is likely to be used inappropriately-the Web sites promote self-diagnosis and self-medication, and antibiotics are likely to be used in inappropriate dosages. No prescription was required, and no online consultation was necessary. Fourth, we have limited our count to English language websites. The first 300 search results of on both sites were examined to identify vendors for antibiotics that did not require a prescription. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance. This decrease was interpreted as evidence that the full use of antibiotics was also reduced. Thus, as soon as patients receive over-the-counter antibiotics and self-treating self-limiting illnesses with drugs, such as upper-respiratory tract infections without complications, they are likely to suggest that the antibiotic was effective, and self-medicate in the future. The purpose of this study was to examine antibiotics available to patients without a prescription, a phenomenon on the Internet. Reducing inappropriate use of antibiotics is key to many antibiotic resistance initiatives. Our study suggests that the opposite might be the case. We classified Web sites of vendors according to several variables. As some vendors have multiple URLs to reach their company, we checked the mailing address, title and phone number to avoid double counting. Our purchase arrived from Mexico with no information on instructions for use of the medication. All these obstacles cause the illegal acquisition of antibiotics by patients. First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication.