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Moreover, pharmaceutical companies may need to monitor who is selling their products and through what mechanisms. Recent evidence in ethnic communities in the United States indicates a high level of self-medication with antibiotics either obtained without a prescription in a foreign country and imported into the United States or acquired in the United States without a prescription at stores in ethnic communities. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication. We compared identifying telephone numbers, street addresses, and site headers for each site as a way to sort out duplication. We assessed whether individuals could purchase penicillins, macrolides, fluoroquinolones, and cephalosporins, because the availability of multiple classes of antibiotics would affect additional selective pressure in the community. Although the vast majority of websites were in English, some were in other languages. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance. Second, there was a considerable repetition in the Web sites, which made an accurate determination of unique vendors from the 184 different sites difficult, an effort that may have let to some error. Third, we categorized the classes of antibiotics available for purchase. Our final list of URLs included 184 links to single vendors of antibiotics. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. The links to these advertised sites were also investigated. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary.