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The links to these advertised sites were also investigated. Thus, vendors targeting foreign-language speakers in the United States would have been missed. As websites appear and disappear at a relative frequency, searches and classifications were performed during the first week of September 2008. The vendors identified in this study do not appear to be fearful of prosecution. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each. We therefore wanted to find out if the amount of time between online evaluation and getting treatment was significantly longer. In usual face-to-face health care visits for respiratory tract infections during which antibiotics are prescribed, more than 90% of prescriptions are filled on the day of the office visit. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed. Our study suggests that the opposite might be the case. Third, we categorized the classes of antibiotics available for purchase. The medical community and the public health and regulating agencies, as well as pharmaceutical companies, need to expand efforts to control antibiotic resistance beyond initiatives centered on prescribing behavior to include self-medication and sources of antibiotics obtained without prescription. Fourth, we categorized whether a person could buy antibiotics, especially broad-spectrum antibiotics, in quantities greater than what would be considered adequate 1 course of treatment for acute respiratory tract infection. Reducing inappropriate use of antibiotics is key to many antibiotic resistance initiatives. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance.