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Fifth, we estimated the expected delivery time to take antibiotics. Second, we examined whether the vendor would ship prescription antibiotics to a buyer in the United States, as well as several other countries (Canada, United Kingdom) where antibiotics are available only by prescription. The links to these advertised sites were also investigated. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. There are several limitations to this study. This reservoir of antibiotics is likely to be used inappropriately-the Web sites promote self-diagnosis and self-medication, and antibiotics are likely to be used in inappropriate dosages. If those who are self-medicating are taught that they put their own health at risk, they may be less likely to use these online pharmacies. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. As some vendors have multiple URLs to reach their company, we checked the mailing address, title and phone number to avoid double counting. Thus, as soon as patients receive over-the-counter antibiotics and self-treating self-limiting illnesses with drugs, such as upper-respiratory tract infections without complications, they are likely to suggest that the antibiotic was effective, and self-medicate in the future. This decrease was interpreted as evidence that the full use of antibiotics was also reduced. No prescription was required, and no online consultation was necessary. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents. The vendors identified in this study do not appear to be fearful of prosecution. This activity suggests that some vendors are aware of the questionable legitimacy of their business.