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Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. The medical community and the public health and regulating agencies, as well as pharmaceutical companies, need to expand efforts to control antibiotic resistance beyond initiatives centered on prescribing behavior to include self-medication and sources of antibiotics obtained without prescription. Unfortunately, this strategy of focusing on prescribing practices does not address the behavior of self-medication with antibiotics. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. In conclusion, antibiotics are freely available for purchase over the Internet without a prescription, and the general structure of transactions encourages self-medication and poor quality care. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. This phenomenon has not been the focus of initiatives to control antibiotic resistance. Although more than half of the identified sites provided online consultation for prescribing, the lack of interaction between the patient and the doctor did not lead to any opportunity for patient education. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. No prescription was required, and no online consultation was necessary. Other providers are trying to upset this law by providing online diagnoses and prescriptions based on medical records without a physical examination and without a long relationship between the patient and the doctor, a practice that is not considered an adequate standard of care. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each.