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Unfortunately, this strategy of focusing on prescribing practices does not address the behavior of self-medication with antibiotics. Our study suggests that the opposite might be the case. We therefore wanted to find out if the amount of time between online evaluation and getting treatment was significantly longer. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior. Second, we examined whether the vendor would ship prescription antibiotics to a buyer in the United States, as well as several other countries (Canada, United Kingdom) where antibiotics are available only by prescription. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary. Third, we categorized the classes of antibiotics available for purchase. To examine the types of Web sites and vendors dispensing antibiotics on the Internet, we conducted a search using 2 major search engines (Google and Yahoo) and the key words "purchase antibiotics without prescription" and "online (English only). As some vendors have multiple URLs to reach their company, we checked the mailing address, title and phone number to avoid double counting. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. We assessed whether individuals could purchase penicillins, macrolides, fluoroquinolones, and cephalosporins, because the availability of multiple classes of antibiotics would affect additional selective pressure in the community. The extended delay between diagnosis and treatment receipt has consequences for resolving self-limiting conditions and storing unused treatment. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance.