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This decrease was interpreted as evidence that the full use of antibiotics was also reduced. Our final list of URLs included 184 links to single vendors of antibiotics. We classified Web sites of vendors according to several variables. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed. Some Internet vendors also attempt to skirt US regulations by operating in countries outside the United States but marketing to US consumers. The frequency of relevant Web sites declined substantially after the first 300. Fifth, we estimated the expected delivery time to take antibiotics. Fourth, we categorized whether a person could buy antibiotics, especially broad-spectrum antibiotics, in quantities greater than what would be considered adequate 1 course of treatment for acute respiratory tract infection. Fourth, we have limited our count to English language websites. All these obstacles cause the illegal acquisition of antibiotics by patients. If those who are self-medicating are taught that they put their own health at risk, they may be less likely to use these online pharmacies. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. Since the websites suggested a range of days for the expected treatment receipt, we used the median to represent the expected delivery time. Third, we categorized the classes of antibiotics available for purchase.