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Patients are increasingly using the Internet not only to access health information but also to obtain medication. There are several limitations to this study. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance. To examine the types of Web sites and vendors dispensing antibiotics on the Internet, we conducted a search using 2 major search engines (Google and Yahoo) and the key words "purchase antibiotics without prescription" and "online (English only). First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. Our final list of URLs included 184 links to single vendors of antibiotics. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. Previous research suggests that a patient's past experience of care seeking and treatment use influences future expectations for treatment of respiratory tract infections. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. Thus, vendors targeting foreign-language speakers in the United States would have been missed. The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. Because of its effect on morbidity and mortality, antibiotic resistance is considered a threat to US health and national security by the Institute of Medicine and the Infectious Diseases Society of America. Although providing over-the-counter drugs is illegal in the United States, failure to enforce US laws likely encourages these companies to sell their products to patients. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior.