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The extended delay between diagnosis and treatment receipt has consequences for resolving self-limiting conditions and storing unused treatment. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication. This activity suggests that some vendors are aware of the questionable legitimacy of their business. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. Several studies suggest that antibiotic prescribing for viral illnesses, respiratory tract infections being one example, has declined in the last decade. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. There are several limitations to this study. Although the vast majority of websites were in English, some were in other languages. All these obstacles cause the illegal acquisition of antibiotics by patients. Fifth, we estimated the expected delivery time to take antibiotics. Other providers are trying to upset this law by providing online diagnoses and prescriptions based on medical records without a physical examination and without a long relationship between the patient and the doctor, a practice that is not considered an adequate standard of care. Third, we categorized the classes of antibiotics available for purchase. In addition, the ability of Internet-based companies to exist without an identifiable physical location or property makes the location and writing of FDA instructions extremely difficult. Thus, vendors targeting foreign-language speakers in the United States would have been missed. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs.