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If those who are self-medicating are taught that they put their own health at risk, they may be less likely to use these online pharmacies. Finally, in order to determine whether these sites actually provide a product that they intended to sell over the counter, we submitted an online order to 1 vendor for 6 tablets of azithromycin, 500 mg each. We assessed whether individuals could purchase penicillins, macrolides, fluoroquinolones, and cephalosporins, because the availability of multiple classes of antibiotics would affect additional selective pressure in the community. In usual face-to-face health care visits for respiratory tract infections during which antibiotics are prescribed, more than 90% of prescriptions are filled on the day of the office visit. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. For this second group, no prescription from a doctor or clinical physician was necessary before gaining access to the site. Self-administration of antibiotics occurs in all countries, but it is particularly problematic where the use of antimicrobials without a prescription is encouraged by the lack of laws restricting antibiotic sales or a failure to enforce the laws. This phenomenon has not been the focus of initiatives to control antibiotic resistance. The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. We therefore wanted to find out if the amount of time between online evaluation and getting treatment was significantly longer. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. First, although all of the included providers would sell antibiotics without a prescription, we assessed whether the supplier would sell antibiotics without any form of prescription or whether a prescription created for the purchase based on the completion of an online medical history was required. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed. Moreover, pharmaceutical companies may need to monitor who is selling their products and through what mechanisms. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations.