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Thus, as soon as patients receive over-the-counter antibiotics and self-treating self-limiting illnesses with drugs, such as upper-respiratory tract infections without complications, they are likely to suggest that the antibiotic was effective, and self-medicate in the future. As part of this study, we bought over-the-counter antibiotics over the counter. Second, there was a considerable repetition in the Web sites, which made an accurate determination of unique vendors from the 184 different sites difficult, an effort that may have let to some error. Some Internet vendors also attempt to skirt US regulations by operating in countries outside the United States but marketing to US consumers. As a result, most community assessments of antibiotic reservoirs are based on assessments by prescribing clinician behavior. Previous research suggests that a patient's past experience of care seeking and treatment use influences future expectations for treatment of respiratory tract infections. We compared identifying telephone numbers, street addresses, and site headers for each site as a way to sort out duplication. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. Finally, in order to determine whether these sites actually provide a product that they intended to sell over the counter, we submitted an online order to 1 vendor for 6 tablets of azithromycin, 500 mg each. If those who are self-medicating are taught that they put their own health at risk, they may be less likely to use these online pharmacies. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. Third, we could not to determine how often pharmaceuticals purchased over the Internet were not genuine, inactive, out of date, or adulterated. In conclusion, antibiotics are freely available for purchase over the Internet without a prescription, and the general structure of transactions encourages self-medication and poor quality care.