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The frequency of relevant Web sites declined substantially after the first 300. Unfortunately, other disturbing evidence suggests that this problem may not be easily fixed through education, a troubling issue in controlling antibiotic use. We therefore wanted to find out if the amount of time between online evaluation and getting treatment was significantly longer. This study was not meant to be an exhaustive census of these sites, primarily because with the questionable legality of some of these practices, these sites rapidly come and go. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. Most initiatives, however, focus almost exclusively on controlling prescribing by health care clinicians and do not focus on patient self-medication. Several studies suggest that antibiotic prescribing for viral illnesses, respiratory tract infections being one example, has declined in the last decade. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents. The vendors identified in this study do not appear to be fearful of prosecution. As some vendors have multiple URLs to reach their company, we checked the mailing address, title and phone number to avoid double counting. Third, we categorized the classes of antibiotics available for purchase. Our study suggests that the opposite might be the case. No prescription was required, and no online consultation was necessary. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations.