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Unfortunately, this strategy of focusing on prescribing practices does not address the behavior of self-medication with antibiotics. Thus, vendors targeting foreign-language speakers in the United States would have been missed. Fifth, we estimated the expected delivery time to take antibiotics. Unfortunately, other disturbing evidence suggests that this problem may not be easily fixed through education, a troubling issue in controlling antibiotic use. As part of this study, we bought over-the-counter antibiotics over the counter. Although more than half of the identified sites provided online consultation for prescribing, the lack of interaction between the patient and the doctor did not lead to any opportunity for patient education. Our final list of URLs included 184 links to single vendors of antibiotics. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. Our study is the first to document this phenomenon, and we describe the mechanism for purchasing antibiotics online; future studies will need to document the scope of antibiotics purchased through this mechanism to better understand its direct implications for antibiotic resistance. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. Our study suggests that the opposite might be the case. If those who are self-medicating are taught that they put their own health at risk, they may be less likely to use these online pharmacies. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents.