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Self-administration of antibiotics occurs in all countries, but it is particularly problematic where the use of antimicrobials without a prescription is encouraged by the lack of laws restricting antibiotic sales or a failure to enforce the laws. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. The medical community and the public health and regulating agencies, as well as pharmaceutical companies, need to expand efforts to control antibiotic resistance beyond initiatives centered on prescribing behavior to include self-medication and sources of antibiotics obtained without prescription. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. No prescription was required, and no online consultation was necessary. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. First, although all of the included providers would sell antibiotics without a prescription, we assessed whether the supplier would sell antibiotics without any form of prescription or whether a prescription created for the purchase based on the completion of an online medical history was required. Most initiatives, however, focus almost exclusively on controlling prescribing by health care clinicians and do not focus on patient self-medication. There are several limitations to this study. All these obstacles cause the illegal acquisition of antibiotics by patients. Although excessive consumption of antibiotics has contributed to the spread of antibiotic resistance, 4-6 most initiatives regarding inappropriate direct human consumption of the antibiotic therapy center are almost exclusively controlled by prescribing by healthcare clinicians. Patients are increasingly using the Internet not only to access health information but also to obtain medication. The frequency of relevant Web sites declined substantially after the first 300. In our analysis of evidence of the concept of buying 6 tablets of azithromycin, 500 mg each. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. Although the vast majority of websites were in English, some were in other languages.