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Our study suggests that the opposite might be the case. As part of this study, we bought over-the-counter antibiotics over the counter. In the case of online histories to justify a prescription, we assumed that individuals are primarily purchasing antibiotics for an acute problem. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. This reservoir of antibiotics is likely to be used inappropriately-the Web sites promote self-diagnosis and self-medication, and antibiotics are likely to be used in inappropriate dosages. In conclusion, antibiotics are freely available for purchase over the Internet without a prescription, and the general structure of transactions encourages self-medication and poor quality care. As some vendors have multiple URLs to reach their company, we checked the mailing address, title and phone number to avoid double counting. Several studies suggest that antibiotic prescribing for viral illnesses, respiratory tract infections being one example, has declined in the last decade. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. Our final list of URLs included 184 links to single vendors of antibiotics. Previous research suggests that a patient's past experience of care seeking and treatment use influences future expectations for treatment of respiratory tract infections. Increased regulation of sites outside of controlled substances to include antibiotics seems guaranteed and necessary. The first 300 search results of on both sites were examined to identify vendors for antibiotics that did not require a prescription. There are several limitations to this study. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. Unfortunately, other disturbing evidence suggests that this problem may not be easily fixed through education, a troubling issue in controlling antibiotic use.