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The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. The purpose of this study was to examine antibiotics available to patients without a prescription, a phenomenon on the Internet. In some cases the URL did not take the reader to an actual medication vendor; rather, the Web site contained multiple advertisements and links to other sites for purchasing antibiotics. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. Thus, vendors targeting foreign-language speakers in the United States would have been missed. In addition, the ability of Internet-based companies to exist without an identifiable physical location or property makes the location and writing of FDA instructions extremely difficult. Although more than half of the identified sites provided online consultation for prescribing, the lack of interaction between the patient and the doctor did not lead to any opportunity for patient education. Unfortunately, this strategy of focusing on prescribing practices does not address the behavior of self-medication with antibiotics. We therefore wanted to find out if the amount of time between online evaluation and getting treatment was significantly longer. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. Third, we could not to determine how often pharmaceuticals purchased over the Internet were not genuine, inactive, out of date, or adulterated. Previous research suggests that a patient's past experience of care seeking and treatment use influences future expectations for treatment of respiratory tract infections. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication. The vendors identified in this study do not appear to be fearful of prosecution.