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Most initiatives, however, focus almost exclusively on controlling prescribing by health care clinicians and do not focus on patient self-medication. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. Our purchase arrived from Mexico with no information on instructions for use of the medication. To examine the types of Web sites and vendors dispensing antibiotics on the Internet, we conducted a search using 2 major search engines (Google and Yahoo) and the key words "purchase antibiotics without prescription" and "online (English only). The frequency of relevant Web sites declined substantially after the first 300. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. Since the websites suggested a range of days for the expected treatment receipt, we used the median to represent the expected delivery time. After completing the online medical history, the customer would be given a prescription that would allow the purchase to be completed. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. Patients are increasingly using the Internet not only to access health information but also to obtain medication. The extended delay between diagnosis and treatment receipt has consequences for resolving self-limiting conditions and storing unused treatment. That these companies can be located in countries outside US jurisdictions complicates enforcement of US laws. The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. Antibiotic resistance is a common problem, however, and has been described with numerous infectious agents and in varying contexts. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations.