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We compared identifying telephone numbers, street addresses, and site headers for each site as a way to sort out duplication. Third, we categorized the classes of antibiotics available for purchase. This phenomenon has not been the focus of initiatives to control antibiotic resistance. For example, we found that servers at Dartmouth College, East Carolina University, University of Pittsburgh, Carnegie Mellon University, and California State University in San Francisco were all used, most likely without their knowledge, to be reassigned to online pharmacies. In addition, the ability of Internet-based companies to exist without an identifiable physical location or property makes the location and writing of FDA instructions extremely difficult. No prescription was required, and no online consultation was necessary. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. Third, we could not to determine how often pharmaceuticals purchased over the Internet were not genuine, inactive, out of date, or adulterated. The purpose of this study was to examine antibiotics available to patients without a prescription, a phenomenon on the Internet. The links to these advertised sites were also investigated. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. First, although all of the included providers would sell antibiotics without a prescription, we assessed whether the supplier would sell antibiotics without any form of prescription or whether a prescription created for the purchase based on the completion of an online medical history was required.