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As websites appear and disappear at a relative frequency, searches and classifications were performed during the first week of September 2008. Antibiotics serve a useful therapeutic purpose in treating and controlling the effects of infectious agents. For example, we found that servers at Dartmouth College, East Carolina University, University of Pittsburgh, Carnegie Mellon University, and California State University in San Francisco were all used, most likely without their knowledge, to be reassigned to online pharmacies. Patients are increasingly using the Internet not only to access health information but also to obtain medication. European countries struggled with the problem of self-medication with antibiotics and found that the belief in the appropriateness of self-medication with antibiotics for bronchitis and the perceived availability of antibiotics without a prescription was associated with an increased likelihood of self-medication. Other providers are trying to upset this law by providing online diagnoses and prescriptions based on medical records without a physical examination and without a long relationship between the patient and the doctor, a practice that is not considered an adequate standard of care. Specifically, we classified a single course of azithromycin as 6 pills, 250 mg each. We classified Web sites of vendors according to several variables. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. In the case of online histories to justify a prescription, we assumed that individuals are primarily purchasing antibiotics for an acute problem. The extent to which antibiotics are available for over-the-counter purchases over the Internet is unknown. This phenomenon has not been the focus of initiatives to control antibiotic resistance. Our purchase arrived from Mexico with no information on instructions for use of the medication. If patients who are now denied antibiotics through their physician can access over-the-counter medications, the overall level of antibiotic use in the general population can actually increase and thus have a significant effect on rates of resistance to microbial degradation. Clinicians evaluating the patient's use of self-medication when taking a medical history may function as an important opportunity to tell patients about not only antibiotic resistance, but also potential interactions between antibiotics and other prescription drugs. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only.