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The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. Patients are increasingly using the Internet not only to access health information but also to obtain medication. This phenomenon has not been the focus of initiatives to control antibiotic resistance. We classified Web sites of vendors according to several variables. The medical community and the public health and regulating agencies, as well as pharmaceutical companies, need to expand efforts to control antibiotic resistance beyond initiatives centered on prescribing behavior to include self-medication and sources of antibiotics obtained without prescription. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. Moreover, pharmaceutical companies may need to monitor who is selling their products and through what mechanisms. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. Although excessive consumption of antibiotics has contributed to the spread of antibiotic resistance, 4-6 most initiatives regarding inappropriate direct human consumption of the antibiotic therapy center are almost exclusively controlled by prescribing by healthcare clinicians. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. First, this study provides a sample of websites and providers, and thus may not be indicative of all suppliers selling over-the-counter antibiotics. In addition, the available quantities and the interval between prescribing and receiving treatment suggest that these transactions will likely be used by people storing drugs for future self-diagnosis and treatment, or for sale. Fifth, we estimated the expected delivery time to take antibiotics. Second, we examined whether the vendor would ship prescription antibiotics to a buyer in the United States, as well as several other countries (Canada, United Kingdom) where antibiotics are available only by prescription. This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. Unfortunately, other disturbing evidence suggests that this problem may not be easily fixed through education, a troubling issue in controlling antibiotic use.