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This practice also occurs in the United States even though the United States regulates the acquisition of antibiotics, which will be limited by prescription only. Further education aimed at patients and the community, as well as increased regulation and application of existing guidelines, can help control this potentially vast reservoir of antibiotics. Unfortunately, this strategy of focusing on prescribing practices does not address the behavior of self-medication with antibiotics. Our purchase arrived from Mexico with no information on instructions for use of the medication. Although the vast majority of websites were in English, some were in other languages. This phenomenon has not been the focus of initiatives to control antibiotic resistance. Even with these strategies, however, it was difficult to know whether one corporation still owns and manages several locations. The US Food and Drug Administration forbids ordering prescription drugs from outside the United States: Thus, in virtually all instances, individual citizens are prohibited from importing prescription drugs into the United States. The findings described in this study suggest that there is a potentially large pool of antibiotics in the United States that is not affected by initiatives to change physician-prescribing practices and may be contributing to antibiotic resistance. The first 300 search results of on both sites were examined to identify vendors for antibiotics that did not require a prescription. Third, we categorized the classes of antibiotics available for purchase. We considered more than 6 pills to be excessive and could lead to future self-medication with the unused pills. Second, we examined whether the vendor would ship prescription antibiotics to a buyer in the United States, as well as several other countries (Canada, United Kingdom) where antibiotics are available only by prescription. Reducing inappropriate use of antibiotics is key to many antibiotic resistance initiatives. In the case of online histories to justify a prescription, we assumed that individuals are primarily purchasing antibiotics for an acute problem.